Dr. Zaoutis's research focuses on healthcare-acquired infections and antibiotic resistance. Within the area of healthcare-acquired infections, he is particularly interested in fungal infections. His work also focuses on pediatric pharmacoepidemiology as it relates to the judicious use of antimicrobial agents (antimicrobial stewardship), both in the hospital and in ambulatory care. Finally, Dr. Zaoutis is associate director of the Center for Pediatric Clinical Effectiveness Research at the Children’s Hospital of Philadelphia. The center promotes research on how to best manage pediatric illness, disseminates knowledge gained from research, and partners with other groups to implement best practices to improve the quality of care delivered to children.