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Yun Li, PhD

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Yun Li, PhD

Associate Professor of Biostatistics

Dr. Li conducts methodological research in causal inference, unmeasured confounding, missing data, mediation, Bayesian analyses and survey methods. She has led the effort in database management, data integrity, rigorous and robust analytical methods in many multicenter studies and NIH-funded program projects in biomedical science, in areas including including breast cancer, prostate cancer, head-and-neck cancer, kidney disease, cardiovascular diseases and liver disease in the past two decades.  

Needs that arose in the course of her collaborative work have inspired her to innovate in statistical methods research, and she has led the development of statistical methods to tackle the statistical issues in these clinical studies. Her methodological work has involved four key areas: 1) intermediate outcomes; 2) time-dependent treatments; 3) unmeasured confounders; and 4) missing data. Of note, her early methods work was among the first to propose a causal inference framework for evaluating surrogate endpoints, such as intermediate biomarkers, surrogate markers or mediators.  

Prior to her work at Penn, Dr. Li was a Research Associate Professor at the University of Michigan (UM). Dr. Li earned her PhD in Biostatistics from UM, following a period of highly effective collaborative work at Duke University Clinical Research Institute. She joined the UM Biostatistics faculty as a Research Assistant Professor after graduation.

Content Area Specialties

Infectious disease and pediatric medicine, breast cancer, kidney disease, cardiovascular disease.

Methodology Specialties

Causal inference, unmeasured confounding, missing data, mediation, Bayesian analyses and survey methods

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